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N-Acetyl Semax Amidate 30mg
Cognitive

N-Acetyl Semax Amidate 30mg

4.4 (320 reviews)

Nootropic research compound for cognitive studies.

Semax is a synthetic heptapeptide derived from ACTH(4-10), developed in Russia as a nootropic and neuroprotective research compound. It has a substantial literature base in cognitive, stroke-recovery, and BDNF-modulation research.

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Proposed mechanism

Semax upregulates BDNF and NGF expression in rodent brain research, and modulates dopaminergic and serotonergic signaling. It has been studied across learning, memory, and post-ischemic-recovery models.

Research highlights

  • Derived from ACTH(4-10) — the non-corticotropic fragment
  • Strong BDNF/NGF upregulation in research models
  • N-Acetyl Semax Amidate version offers extended stability
  • One of the most extensively studied Russian research nootropics

Research protocol notes

Intranasal delivery is standard in Russian research protocols. Injectable routes also appear. N-Acetyl Semax Amidate is preferred for longer research windows.

Stacking and comparative studies

Often compared to or paired with Selank in cognitive-research designs.

Handling and storage

Lyophilized powder is stable at ambient shipping temperatures. Once reconstituted with bacteriostatic water, store at 2–8 °C and use within 28 days. For long-term storage of unreconstituted vials, freeze at −20 °C and protect from light.

Frequently asked

What is N-Acetyl Semax Amidate?

A stabilized form of Semax with both N-terminal acetylation and C-terminal amidation — improved half-life for longer protocols.

How does Semax compare to Selank?

Semax is more cognitive/neurotrophic; Selank is more anxiolytic. Related research lineages but different research applications.

What is BDNF?

Brain-Derived Neurotrophic Factor — a key growth factor in neuronal survival and synaptic plasticity. Semax is one of the more potent research peptides for BDNF upregulation.

Injectable or intranasal?

Intranasal is standard in the Russian research tradition; injectable protocols also appear.

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