Buy 5-Amino-1MQ — 5 mg Lyophilized Vial
Metabolic-rate investigations — structured for incretin receptor pharmacology.
5-Amino-1MQ is a small-molecule inhibitor of NNMT (nicotinamide N-methyltransferase), an enzyme central to NAD+ salvage and methyl-donor balance. It is actively studied in obesity, metabolic, and sarcopenia research.
Reconstitution volumes
Volumes of bacteriostatic water required to dissolve each vial at common research concentrations.
| Vial | at 2 mg/mL | at 5 mg/mL | at 10 mg/mL |
|---|---|---|---|
| 5 mg | 2.50 mL | 1 mL | 0.50 mL |
| 50 mg | 25 mL | 10 mL | 5 mL |
Numbers are calculated from the stated vial mass. Verify against the supplier's instructions for your specific research protocol.
Available sizes
Key facts
- NNMT inhibitor — small molecule, not a peptide
- Raises NAD+ precursor availability via NNMT blockade
- Studied in adipocyte, muscle, and metabolic research
- Available in oral capsule and injectable research formats
Mechanism in the literature
NNMT consumes both nicotinamide (an NAD+ precursor) and SAM (the universal methyl donor). Inhibiting NNMT raises nicotinamide availability for NAD+ synthesis and preserves SAM pools — a mechanism proposed to support both metabolic and muscle-biology endpoints.
Often paired with
Buyers viewing 5-Amino-1MQ typically also consider Tesofensine Capsules, Cagrilintide and AOD9604. Each is in stock, sealed under nitrogen with a lot-matched CoA.
Research use-cases
- NNMT inhibitor — small molecule, not a peptide
- Raises NAD+ precursor availability via NNMT blockade
- Studied in adipocyte, muscle, and metabolic research
- Available in oral capsule and injectable research formats
Handling in the lab
Both oral and injectable research routes appear in the literature. Oral capsule formats are convenient for multi-week protocols.
Stacking and paired-compound work
Comparative protocols sometimes combine 5-Amino-1MQ with direct NAD+ supplementation to study combined NNMT-blockade and NAD+-repletion effects.
Storage and shelf-life
Lyophilized powder is stable at ambient shipping temperatures. Once reconstituted with bacteriostatic water, store at 2–8 °C and use within 28 days. For long-term storage of unreconstituted vials, freeze at −20 °C and protect from light.
Frequently asked
Is 5-Amino-1MQ a peptide?
No — it is a small-molecule NNMT inhibitor (a quinoline derivative), not a peptide. It appears in peptide-research catalogs because it targets NAD+-adjacent biology.
What is NNMT?
Nicotinamide N-methyltransferase — an enzyme that consumes nicotinamide and SAM to produce N-methylnicotinamide. Elevated NNMT activity is linked to obesity in research models.
Oral or injectable?
Both formats are used. Oral capsules suit longer research windows; injectable is used when fast PK is desired.
How does it interact with NAD+ supplementation?
NNMT blockade increases the nicotinamide pool available for NAD+ synthesis — a complementary mechanism to direct NAD+/NMN supplementation.
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