Ipamorelin 10mg
Studied for growth-axis and performance research.
Ipamorelin is a selective growth-hormone secretagogue and ghrelin-receptor agonist. Among GHRPs, it is noted in the research literature for its selectivity — stimulating GH release with minimal impact on cortisol or prolactin in the rodent models where it has been characterized.
Proposed mechanism
Ipamorelin binds the GHS-R1a (ghrelin) receptor in the anterior pituitary, triggering pulsatile growth-hormone release. Unlike earlier GHRPs such as GHRP-2 and GHRP-6, ipamorelin shows limited activity on the HPA axis in research, which is the basis for its "clean" reputation in comparative studies.
Research highlights
- Selective GH release — minimal cortisol/prolactin impact in research
- Short half-life (~2 hours) supporting pulsatile dosing studies
- Commonly stacked with CJC-1295 for sustained GH-axis research
- One of the most widely studied secretagogues in the pentapeptide class
Research protocol notes
A 10 mg vial reconstituted in 2 mL BAC water yields 5 mg/mL. Multiple-daily protocols are common in GH-pulse research.
Stacking and comparative studies
Ipamorelin + CJC-1295 is the canonical growth-axis research stack — CJC-1295 as the GHRH-analog driver, ipamorelin as the ghrelin-pathway amplifier. Ipamorelin + Tesamorelin is another well-characterized pairing.
Handling and storage
Lyophilized powder is stable at ambient shipping temperatures. Once reconstituted with bacteriostatic water, store at 2–8 °C and use within 28 days. For long-term storage of unreconstituted vials, freeze at −20 °C and protect from light.
Frequently asked
Why combine ipamorelin with CJC-1295?
They target complementary receptors — GHRH and ghrelin — and research reports synergistic GH release when the two pulses are aligned.
How selective is ipamorelin compared to GHRP-6?
Research shows substantially less cortisol/prolactin elevation with ipamorelin than with GHRP-6 at comparable GH-release endpoints.
What is the typical half-life?
Around 2 hours in research models, supporting multi-daily pulsed protocols.
Is a COA included?
Yes — per-lot independent testing is standard.
